Gland Type In-situ Fruit Freeze Drying Machine

About This Product

● Drying area: 0.1㎡
● Number of shelves: 1 layer
● Shelf temperature range: -50℃～65℃
● Shelf spacing: 70mm
● Shelf size: 265mm*400mm*25mm
● Ф22 vials: 220 pcs
● Ф16 vials: 434 pcs
● Ф12 vials: 777 pcs
● Cold trap low temperature: ≤-55℃ (no load)
● Water capture capacity: 3-5kg/24h
● Plate liquid: 1L
● Ultimate vacuum: ≤10Pa
● Capping method: manual
● Cooling method: air cooling, good ventilation, room temperature ≤25℃
● Overall dimensions: 605*610*(1200+130 capping handle height) (mm)

         The in-situ freeze dryer is an advanced freeze drying equipment that can complete the entire process of freezing, drying and sealing samples in a closed system. The design of the in-situ freeze dryer is particularly suitable for applications that require a highly controlled and sterile environment, such as pharmaceuticals, biotechnology, food and laboratory research. The following is a detailed introduction to the in-situ freeze dryer:

Design and functional features

• In-situ operation: The biggest feature of the in-situ freeze dryer is that all operations are completed in a closed system. From freezing to drying to sealing, the sample is carried out in the same container or drying chamber, avoiding the transfer of samples between different processing stages and reducing the risk of contamination.
• Closed system: The equipment has a completely closed working environment and can perform drying and sealing operations under sterile and oxygen-free conditions. This design is particularly suitable for processing sensitive samples such as drugs, vaccines, proteins, etc. to ensure the purity and stability of the samples.
• Precise control: The in-situ freeze dryer is equipped with a high-precision control system that can accurately adjust the temperature, vacuum and time to ensure the stability and repeatability of the drying process.
• High degree of automation: The equipment usually has a highly automated operating process, from sample loading to drying completion and sealing, which can be automatically completed through preset programs, greatly reducing manual intervention and improving production efficiency.

Working principle

The working process of the in-situ freeze dryer usually includes the following main stages:

• Freezing stage: The sample is first quickly frozen to an extremely low temperature in the dryer to freeze the water in the sample. This process is usually completed in a drying chamber, and the equipment's refrigeration system is responsible for maintaining a low temperature environment.
• Sublimation drying stage: Under vacuum conditions, ice sublimates directly into water vapor and is discharged from the drying chamber through a vacuum pump. This process requires precise control of temperature and vacuum to ensure smooth sublimation while maintaining the physical and chemical stability of the sample.
• Capping and sealing stage: After drying is completed, the equipment caps and seals the sample in a vacuum or inert gas environment. This process can be completed in situ without transferring the sample, minimizing the risk of contamination.

Equipment components

1. Freezing system: The sample is quickly frozen to the required low temperature through compressor refrigeration, usually including condenser and evaporator.
2. Vacuum system: It includes high-efficiency vacuum pump and vacuum trap to maintain the low-pressure environment of the drying chamber, help the water sublimate and discharge from the drying chamber.
3. Heating system: Control the heating rate and temperature of the sample to ensure the smooth sublimation process of ice.
4. Control system: Advanced PLC control system or computer control system, used to accurately adjust and monitor parameters such as temperature, vacuum degree, time, etc. during the freeze-drying process.
5. Capping device: The capping device integrated in the dryer is used to seal the sample container.

Application field

1. Pharmaceutical industry: In-situ freeze dryers are widely used in the production and preservation of drugs, especially the freeze-drying of injections, vaccines and biological products.
2. Biotechnology: It is used for the drying and preservation of biological samples, such as proteins, enzymes, antibodies, etc., to ensure the activity and stability of the samples.
3. High-end food: It is suitable for freeze-drying of high-end foods, such as coffee, health products, freeze-dried fruits, etc., to ensure their nutritional content and flavor.
4. Laboratory Research: In scientific research laboratories, in situ freeze dryers are used to process and preserve a variety of samples, especially those that are environmentally sensitive.