Online sterilization of Benchtop Glass Bioreactor System

About This Product

          The sterilization-in-place glass bioreactor is a device specially designed for the biotechnology and pharmaceutical fields. It has the function of sterilizing directly in the reactor without disassembling the reactor. This type of reactor is usually used in fermentation, cell culture, microbiological research and other processes. It can maintain a sterile environment during operation while ensuring the efficiency of experiments and production.

Working Principle

          The sterilization in place glass bioreactor sterilizes the inside of the reactor directly by using high temperature steam or chemical sterilizers, without disassembling or moving the equipment. The sterilization process is usually carried out in a closed system to prevent external contaminants from entering the reactor. The equipment is also equipped with an automated control system that can accurately monitor the sterilization time and temperature to ensure that all microorganisms or impurities are completely removed.

Design Features

• Transparent glass material: The reactor is made of high temperature and pressure resistant glass, allowing the operator to observe the reaction process in real time, while facilitating cleaning and sterilization.
• In-place sterilization function: There is no need to remove the reactor from the system or disassemble it. The sterilization operation can be completed directly in the equipment, reducing downtime and improving production efficiency.
• Precision control system: Equipped with an automated control system that can monitor parameters such as temperature, pressure and time to ensure the accuracy and consistency of the sterilization effect.
• Aseptic operation: After sterilization, the reactor can maintain a sterile environment, which is particularly suitable for fermentation and cell culture processes that require strict aseptic conditions.
• Flexible volume selection: The volume of this type of reactor has suitable models from small-scale laboratory applications to large-scale production to meet different needs.

Main components

1. Reactor body: Made of high-temperature resistant glass, suitable for high-temperature steam or chemical sterilizers, the transparent structure facilitates real-time monitoring of the reaction.
2. Sterilization system: Usually a steam sterilization system is used, which can directly generate high-temperature steam inside the reactor to kill microorganisms.
3. Temperature control system: Precisely control the sterilization temperature to ensure that the sterilization is thorough and will not have adverse effects on the reactor materials or contents.
4. Sensor: Used to detect and record key parameters such as temperature, pressure, pH, etc. to ensure that the environmental conditions in the reactor meet the sterilization requirements.

Application areas

• Pharmaceutical industry: Used for the production of biological drugs, especially antibodies, vaccines, enzyme preparations and other products that require sterile production.
• Biotechnology: Suitable for experiments such as cell culture and genetic engineering, providing a sterile reaction environment to ensure the reliability of experimental results.
• Fermentation industry: In large-scale fermentation processes, sterilization is a key step, and in-situ sterilization reactors can improve production efficiency and output.